Is the hypoxic ventilatory response driven by blood oxygen concentration?

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Is the hypoxic ventilatory response driven by blood oxygen concentration?

Vertebrates breathe faster and deeper when confronted with low oxygen levels in the inspired water or air. The underlying mechanisms for this ubiquitous hypoxic ventilatory response, and the attendant cardiovascular responses, received considerable attention in the latter half of the 19th century. Indeed, the 1938 Nobel Prize in Physiology or Medicine was awarded to Corneille Jean François Heym...

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Time domains of the hypoxic ventilatory response.

The ventilatory response to hypoxia depends on the pattern and intensity of hypoxic exposure and involves several physiological mechanisms. These mechanisms differ in their effect (facilitation or depression) on different components of ventilation (tidal volume and frequency) and in their time course (seconds to years). Some mechanisms last long enough to affect future ventilatory responses to ...

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Does the hypoxic ventilatory response predict the oxygen-induced falls in ventilation in COPD?

The purpose of this study was to determine whether supplemental oxygen-induced decreases in ventilation (VE) and mouth occlusion pressure (P0.1) in patients with COPD are related to the ventilatory or P0.1 responses to hypoxia (delta VE/delta SaO2, delta P0.1/delta SaO2). We measured these responses in 14 patients with a (mean +/- SD) FEV1 of 0.95 +/- .41 L. The VE and P0.1 were also measured w...

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Hypoxic ventilatory response and acute mountain sickness.

The acute ventilatory response to hypoxia (HVR) and to hypercapnia (CO2VR) was measured in 32 members of two mountaineering expeditions prior to their departure. Both teams made rapid ascents to their base camps at 5200 m and 4300 m and remained there for at least four days. Symptom scores for acute mountain sickness (AMS) were collected daily for these four days. There was a range of AMS from ...

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Hypoxic Ventilatory Response and Breathlessness Following Hypocapnic

Study objectives: To investigate the etiology of posthyperventilation (post-HV) hypoxemia following voluntary hyperventilation (VHV), we examined the effects of hypocapnic (hypo-C02) and isocapnic (iso-C02) VHV on the hypoxic ventilatory response (02-response) and on the sensation of breathlessness during the 02-response. Methods: 02-responses and visual analog scale (VAS) scores for estimating...

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ژورنال

عنوان ژورنال: Journal of Experimental Biology

سال: 2017

ISSN: 1477-9145,0022-0949

DOI: 10.1242/jeb.151316